BIOSIT is organizing a day called 3D BIOLOGY with the aim of bringing together researchers and stimulating exchanges and collaborations in the fields of organoids, bioprinting, imaging, tissue culture, organs on chips.

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Program

9:00-16:40

• Video conference reception
• Presentation of Biosit and Biogenouest
• In vitro 3D models for renal cancer research // Yannick Arlot, IGDR, Biosit
• 3D cultures of mammary epithelial cells by orbital shaking // Frédéric Percevault, Irset, “Transcription, environment and cancer” team
• Generation of preclinical models of small cell lung cancer // Rémy Pedeux, COSS, Inserm U1242
• Alginate beads: a new 3D model to mimic the niche of follicular lymphoma? // Frédéric Mourcin, MICMAC, INSERM U1236
  Break
• Extrusion based bioprinting and its application for the creation of a complex multicellular liver model // Marie Cuvellier, Irset, “Dynamique du Micro-Environnement et Cancer” team
• Influence (s) of polycyclic aromatic hydrocarbons on intercellular communication: roles of extracellular vesicles // Eric Le Ferrec, Irset, “Membrane Stress and Signaling” team
• Microsystems and NanoBioanalytical tools for characterization of cellular secretome // Céline Elie-Caille, FEMTO-ST, Besançon
• 3D Bio-printing and Microfluidics: core facility Proposal // Laurent Griscom, Bio3D Technical Manager, UMS Biosit
  12:20 Lunch break
  13: 30 Home
• Microscopy for the observation of living things in 3D and in depth // Xavier Pinson, core facility MRic, Biosit
• 3D reconstruction of a transparent organ section // Nicolas Mouchet, H2P2, Biosit
• Intestinal rare diseases: from C. elegans to mouse organoids // Grégoire Michaux, IGDR
• Modeling early brain development to explore pathophysiology of midline disorders // Erwan Watrin, IGDR
• Neurotoxicity of tramadol on brain organoids // Pierre-Jean Ferron, NuMeCan
  Break
• Study of the pathophysiology of the lens, towards a new 3D model? // David Reboutier & Matthieu Duot, IGDR, “Genetic Expression and Development” team
• Contribution of microfluidics in the long-term maintenance of the functions of the murine testis ex vivo: success story in mice, what about in humans? // Christele Desdoits, Irset, “Physiology and physiopathology of the urogenital tract” team
• Development of human colonic organoids to study epithelial repair in ulcerative colitis // Annaig Lan, NuMeCan
  16:40 Closing

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