GO-EV Colloquium at the Nantes University Scientific Days 2024
Nantes Université organized the 17th edition of the Scientific Days on Tuesday, June 11, 2024 at La Cité des Congrès in Nantes, bringing together 900 participants on site and around a hundred remotely. This event has become an essential annual meeting to promote research and encourage scientific exchanges. For this edition, 18 thematic conferences took place in parallel, allowing researchers to share their progress and reflect on the projects of tomorrow in various scientific disciplines, in line with current and future societal issues.
The GO-EV network took part in this event, with a symposium dedicated to extracellular vesicles (EVs) entitled: Clinical use of extracellular vesicles – Biomarker approach and therapeutic strategies. The symposium provided an opportunity to deepen the application of extracellular vesicles in the clinic, exploring their potential as biomarkers and their integration into innovative therapeutic strategies. More than 130 participants attended varied presentations, with 12 oral presentations, enriching discussions and the “My Vesicles in 180 seconds” challenge.
The event allowed for dynamic exchanges, particularly around the stands of the patrons who support this initiative. The presentations highlighted the current and future challenges of the application of EVs in the clinic, while offering an overview of the projects in development. Highlights of the day included interactions between researchers, the emergence of new collaborative ideas, and research perspectives for the coming years.
The success of this edition demonstrates the growing importance of extracellular vesicles in scientific research and their potential to transform therapeutic and diagnostic approaches. The involvement of the various partner laboratories and companies played a key role in the success of this event.
A rich program and high-level interventions
The GO-EV conference at the Nantes University Scientific Days 2024 took place around three distinct thematic sessions, each offering content-rich presentations.
The first session, “Production and Characterization,” began with presentations by Guillaume Van Niel on live imaging of extracellular vesicles (EVs) and their therapeutic potential, followed by Quentin Roux on the transparency and reproducibility of EV research. Virginie Dehame addressed the characterization of EVs by flow cytometry, while Thibaud Dauphin addressed the large-scale production of spheroid-derived EVs. Hajar Yaakoub completed the session by discussing EVs associated with indole-producing intestinal bacteria, followed by a presentation of IZON Science.
The second session, “EVs and Biomarkers,” focused on the use of EVs in disease diagnosis. Louise Biquard opened the session with a presentation on EVs as biomarkers in liver diseases, followed by Hana Triki who studied sncRNA signatures in EVs from epithelial cells. Baptiste Ganachaud then explored the effects of fecal EVs on the enteric nervous system in autism spectrum disorders. The session concluded with a presentation by MYRIAD.
The third session, “EVs and Clinical Strategies,” highlighted therapeutic strategies involving EVs. Julie Gavard compared the role of plasma EVs to horcruxes. Amanda Silva Brun presented how she moved from research to EVerZom. Alicia Charrier discussed the use of lymph nodes for the study of EV-mediated immune responses. Finally, Judith Lorant presented the use of myoblast-derived EVs to treat Duchenne muscular dystrophy, with an intervention of BECKMAN COULTER to close the session.
These sessions allowed for in-depth discussions on research around EVs, fostering the emergence of new collaborations and ideas in the field.
Another highlight of the day was the “My Vesicles in 180 Seconds” competition, a format where participants had to present their work on EVs in a limited time. This competition offered an opportunity for young researchers to demonstrate their talent and expertise in the field.
- 🥇 Julia Papail, a doctoral student at INRAE, won first prize with her presentation entitled “Deliver'Aureur™: Official supplier of vesicles, as close as possible to your cells”.
- 🥈 Manon Chang, a doctoral student at CRCI2NA, won second place with her presentation on “How do extracellular vesicles from lung cancer disrupt our antitumor immune response?”.
Find the full program for the day: link to the program
Perspectives and Acknowledgments
The GO-EV symposium at the Nantes University Scientific Days 2024 ended on a positive note with promising perspectives for the future of EV research. The open discussions and collaborations initiated during this event will certainly pave the way for new scientific and medical innovations.
We would like to thank Nantes University, Nantes University Foundation, and all the participants for their contribution to the success of this day. The commitment of the speakers made this day an unforgettable moment, rich in discoveries and scientific exchanges.
Thank you to our patrons Beckman Coulter Life Sciences, Izon, MYRIAD, Naobios, Quanterix and SIRIC ILIAD, who contributed to the success of this conference. Thanks also to the laboratories involved, the CRCI2NA, RMeS and CR2TI, who also played a crucial role in organizing and promoting the research presented at this event.
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