The scientific day of the axis was held on November 25, 2024 Structural and metabolomic analysis from GIS BiogenouestThis event aimed to establish interactions between the different technological axes of the network on the theme of data processing and analysis, coming from different sources (mass spectrometry, NMR, chromatography, so-called "omics" approaches and imaging).
The day brought together 70 participants from the various Breton and Loire sites of the network (Rennes, Brest, Roscoff, Fougères, Nantes, Lorient, etc.). The ASM axis core facilities were of course represented (Corsaire, BIBS, Lipidocean), but participation in the day was more widely extended to the various regional research structures (research units, institutes), with the presence of many young researchers.
The meeting covered the different areas of activity of the network (Health, Agro, Sea and Data Science) dear to Biogenouest and various disciplines: Chemistry, Biology, Computer Science, Digital, Mathematics.
Three presentation sessions were offered:
Signal Processing, Data Visualization, and Heterogeneous Data Integration,
with speakers from the network core facilities or collaborators of these same core facilities.
The first session, dedicated to the signal processing, highlighted the importance of this step, which is essential to avoid compromising or biasing the results. The various speakers were able to illustrate this aspect for different types of data, for example for data from GC-c-IRMS for the analysis of fatty acids, or for large volume 3D images.
During the second session devoted to the data visualization, participants were able to measure the extent of the tools developed by the core facilities to allow each user to better exploit their data, sometimes voluminous. The development of these tools involves interactions between biologists and bioinformaticians.
The presentations of the third session were aimed at: heterogeneous data processing, and therefore from different sources. Here again, collaboration between mathematicians, computer scientists, and data specialists with chemists and/or biologists is essential.
An initial presentation made it possible to summarize the challenges of processing heterogeneous data and to open up avenues to better explore and integrate them, emphasizing the importance of networks such as Biogenouest.
Many examples aroused the interest of the assembly:
In the field of Healthcare, 3 different studies were presented, carried out in collaboration with the network core facilities and which showed the integration of transcriptomic and metabolomic data (by NMR, MS) on patient cohorts or cell lines.
In the field of Wed, the study of marine symbioses between bacteria and their hosts was made possible by the integration of MS metabolomics and metabarcoding data.
In the field ofagronomy, combined genetics, genomics and metabolomics approaches were used to study the metabolism of cultivated plants, in partnership with the core facility corsair.
The day's presentations generated many questions and discussions, which continued during the breaks. The richness of the exchanges clearly demonstrates the importance of these scientific days.
